(3-Ethynylphenyl)boronic acid
(3-Ethynylphenyl)boronic acid
CAS: 1189127-05-6
Molecular Formula: C8H7BO2
(3-Ethynylphenyl)boronic acid - Names and Identifiers
(3-Ethynylphenyl)boronic acid - Physico-chemical Properties
| Molecular Formula | C8H7BO2 |
| Molar Mass | 145.95 |
| Density | 1.17±0.1 g/cm3(Predicted) |
| Boling Point | 322.2±44.0 °C(Predicted) |
| pKa | 7.87±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD17677372 |
(3-Ethynylphenyl)boronic acid - Introduction
(3-Ethynylphenyl)boronic acid is an organic boron compound with the chemical formula C8H7BCO2H. The following is an introduction to some properties, uses, methods and safety information about (3-Ethynylphenyl)boronic acid:
Nature:
- (3-Ethynylphenyl)boronic acid is a white solid, soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane.
-It is relatively stable in air, but may decompose under light, oxidants or acidic conditions.
Use:
- (3-Ethynylphenyl)boronic acid is often used as an important reagent in organic synthesis, especially in copper-catalyzed coupling reactions. It can react with aryl bromides or aryl chlorides to form aryl boronic esters.
-Aryl boronic acid esters have a wide range of applications in the field of phenyl substitution, synthesis of spiro compounds, and preparation of important organic molecules.
Preparation Method:
- (3-Ethynylphenyl)boronic acid can be obtained by the chemical reaction of phenylboronic acid. Specific preparation methods include the use of Miyaura-Suzuki coupling reactions, direct nucleophilic substitution reactions, and the like.
Safety Information:
- (3-Ethynylphenyl)boronic acid is generally safe under normal operating conditions, but as an organic compound, some conventional safety measures are still needed.
-When contacting this compound, avoid direct contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical help.
-When using this compound, make sure to conduct the experiment under well-ventilated conditions to avoid inhaling its dust or gas.
-When storing (3-Ethynylphenyl)boronic acid, it should be sealed and stored in a dry and cool place to avoid contact with oxidants and strong acids.
Nature:
- (3-Ethynylphenyl)boronic acid is a white solid, soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane.
-It is relatively stable in air, but may decompose under light, oxidants or acidic conditions.
Use:
- (3-Ethynylphenyl)boronic acid is often used as an important reagent in organic synthesis, especially in copper-catalyzed coupling reactions. It can react with aryl bromides or aryl chlorides to form aryl boronic esters.
-Aryl boronic acid esters have a wide range of applications in the field of phenyl substitution, synthesis of spiro compounds, and preparation of important organic molecules.
Preparation Method:
- (3-Ethynylphenyl)boronic acid can be obtained by the chemical reaction of phenylboronic acid. Specific preparation methods include the use of Miyaura-Suzuki coupling reactions, direct nucleophilic substitution reactions, and the like.
Safety Information:
- (3-Ethynylphenyl)boronic acid is generally safe under normal operating conditions, but as an organic compound, some conventional safety measures are still needed.
-When contacting this compound, avoid direct contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical help.
-When using this compound, make sure to conduct the experiment under well-ventilated conditions to avoid inhaling its dust or gas.
-When storing (3-Ethynylphenyl)boronic acid, it should be sealed and stored in a dry and cool place to avoid contact with oxidants and strong acids.
Last Update：2024-04-10 22:29:15
